A sensuous song of molecular machines.
Support A Capella Science: http://patreon.com/acapellascience
Subscribe! https://www.youtube.com/subscription_center?add_user=acapellascience
Follow Dorothy Andrusiak: https://www.facebook.com/dorothyandrusiak
MP3: https://timblais.bandcamp.com/track/nanobot
—————-
A CAPELLA SCIENCE STUFF:
Patreon: http://patreon.com/acapellascience
Facebook: http://facebook.com/acapellascience
Twitter: http://twitter.com/acapellascience
Instagram: http://instagram.com/acapellascience
Bohemian Gravity poster: https://store.dftba.com/products/bohemian-gravity-poster
Follow me @acapellascience on Twitter, Instagram, Snapchat!
—————-
DOROTHY ANDRUSIAK STUFF:
Facebook: http://facebook.com/dorothyandrusiak
Instagram: https://instagram.com/andrusiak.1/
—————-
EPRSC LINKS:
EPSRC Molecular Robotics program: http://gow.epsrc.ac.uk/NGBOViewGrant.aspx?GrantRef=EP/P027067/1
Prof Dave Leigh group webpage: http://www.catenane.net
—————-
REFERENCES:
[1] http://www.catenane.net/pdfs/articles/2010walker_naturechem.pdf
[2] https://pubs.acs.org/doi/pdf/10.1021/ja058303m
[3] https://www.nature.com/articles/nature05452
[4] https://pubs.acs.org/doi/pdf/10.1021/ja904104c
[5] https://pubs.acs.org/doi/pdf/10.1021/ol102422h
[6] http://pubs.rsc.org/en/content/articlehtml/2016/cc/c6cc08586e
[7] https://www.nature.com/articles/nature23677
[8] http://pubs.rsc.org/en/Content/ArticleLanding/1994/C3/C39940001213#!divAbstract
[9] https://pubs.acs.org/doi/pdf/10.1021/ol0487985
[10] https://pubs.acs.org/doi/pdf/10.1021/ja9712229
[11] http://rotaxane.net/pdfs/articles/Leigh%20Sequential%20Peptide%20Synthesis%20Science%202013.pdf
[12] https://pubs.acs.org/doi/pdf/10.1021/ja908524x
[13] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504628/
[14] https://www.youtube.com/watch?v=b_cp8MsnZFA
[15] https://www.wehi.edu.au/wehi-tv/chromosome-and-kinetochore
[16] https://www.wehi.edu.au/wehi-tv/x-inactivation-and-epigenetics
[17] https://www.wehi.edu.au/wehi-tv/molecular-visualisations-dna
[18] ‘Inner Life of the Cell,’ © 2006 President and Fellows of Harvard College. Created by Alain
Viel, PhD and Robert Lue, PhD in collaboration with XVIVO, LLC and John Liebler, Lead
Animator. Made possible through the generous support of the Howard Hughes Medical
Institution’s Undergraduate Science Education Program.
—————-
NANOBOT
(Music: ‘Havana’ by Camila Cabello)
To plan a nanobot
Map out the molecules to span the nanobot
Add on the motors used to man the nanobot
Signals to talk with a commander
Software and logic’s grammar
Programmed in nanobot
Beginning you better control the movement
(The thermal storm abrew)
Room temperature systems are always moving
(Your system’s moving too)
The pieces and links you pick will
limit
(The states it can assume)
As is it’ll randomly shuffle through them
Now force it with the right
Fuel
Ordered and energetic
A bias in the setup
Adding entropy through
A cycle that’ll let it
Put work to load
Oh na na nanobot
So plan your nanobot
With steps whose opposite’ll jam the nanobot
Barriers free energy expenditure will drop
To let it pass and then to catch it
Go through the door and latch it
A ratchet nanobot
Let’s see
You’ve animated these lil’ gadgets? Damn!
Next let’s see you handle informatics fam
(Nano-informatics)
1-0 the structure of a cache or RAM
Switches are the way to data save and plan (flip it on)
Flip it chemically
Photochemically
Or electrically
Add a flippable knee (then what?)
Make a little more deep
The decisional tree (data)
If you need a calculator how be
Logic gates, like «a, not b»
Input’s a cation, as key (that’s key)
And you get a photon as a reading
So plan your nanobot
To be in part an info scanner nanobot
Reading and writing coded data that allot
Freedom to do as you program it
A Turing automatic
Full gamut nanobot
Doesn’t that look life-like? (x3)
(Break me down I am)
A metananobot
The muse and model of synthetic nanobots
Working in concert as a replicable lot
For all I try to be more than it
Though sentient and organic
I am a nanobot
source